MyBioSource.com's BRD4 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The BRD4 Polyclonal Antibody was generated using BRD4, HUNK1, HUNKI, and PGLS as the antigen and it reacts with Human, Mouse, and Rat.
Description
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15; 19)(q13; p13. 1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described